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JWH-018

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$375.00$3,000.00

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Full Chemical Name: JWH-018

Systematic IUPAC Name: Naphthalen-1-yl-(1-pentylindol-3-yl)methanone

CAS Number: 209414-07-3

ChemSpider Number: 8558143

Molecular Formula: C24H23NO

Molecular Mass: 341.45 g/mol

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Full Chemical Name: Buy JWH-018 online |

Systematic IUPAC Name: Naphthalen-1-yl-(1-pentylindol-3-yl)methanone

CAS Number: 209414-07-3

ChemSpider Number: 8558143

Molecular Formula: C24H23NO

Molecular Mass: 341.45 g/mol

What is JWH 018?

JWH-018 for sale

To begin with, The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06.1 Its effects on suppression of spontaneous activity, maximum possible antinociceptive effect in the tail-flick assay, and rectal temperature are comparable to those of WIN 55,212-2 when tested in rats.

Also .It is a research chemical that belongs to the naphthoylindole family. JWH-081 as all the other research chemicals in the JWH group is a synthetic cannabinoid with analgesic effects. Its full chemical name is 4-methoxynaphthalen- 1-yl- (1-pentylindol- 3-yl)methanone with chemical formula is C25H25NO2 and molecular mass 371.47 g/mol.

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Furthermore JWH-018 is a synthetic cannabinoid found in several versions of the herbal mixture “Spice.” Illicit use of this synthetic cannabinoid centers on its psychoactive effects which mimic those of Δ9-THC in cannabis. While considerably more potent than similar amounts of cannabis, JWH-018 also presents significant challenges for detection by typical Δ9-THC testing assays.

To understand the impact of JWH-018 at molecular and cellular level, we used Saccharomyces cerevisiae as a model. The results showed an increase in yeast growth rate in the presence of this synthetic cannabinoid due to an enhancement in the glycolytic flux at expense of a decrease in pentose phosphate pathway, judging by 2D-Gel proteomic analysis, qRT-PCR experiments and ATP measurements. Overall, our results provide insights into molecular mechanisms of JWH-018 action, also indicating that Saccharomyces cerevisiae is a good model to study synthetic cannabinoids.

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1 review for JWH-018

  1. Jerry Dome

    Is your delivery 100% discreet and safe for me to order ?
    Thanks

    • admin

      Hey jerry we have the best delivery service and discreet drop off both within US and out of States. You can order and 100% sure to receive package

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